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Downregulation of SERPINE1 decreases the tumorigenic capacity of PTX-resistant BC cells in vivo. (A) Image revealing the appearance of tumors from mice that were inoculated with MDA-MB-231/PTX cells with or without SERPINE1 knockdown. (B) Quantification of tumor volumes at the end of the in vivo tumorigenic assays. **P<0.01. SERPINE1, serine protease inhibitor, clade E member 1; PTX, paclitaxel; BC, breast cancer.
