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. 2020 Sep 29;10:552283. doi: 10.3389/fonc.2020.552283

Figure 7.

Figure 7

S100P promotes epithelial mesenchymal transition and tumor proliferation, migration, and invasion. S100P expresses only in malignant tissues and by activation of RAGE and downstream cascades including NF-κB and AP-1–dependent oncogenic mi-RNA activation, which altogether enhanced tumor migration and invasion.