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. 2020 Sep 29;10:573822. doi: 10.3389/fonc.2020.573822

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Copyright © 2020 Liu, Liu, Lyu, Lu, Cui, Wang, Li, Mou, Deng and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expansion of anti-CD19-CAR T-cells and anti-CD19-CAR gene. (A) The average expansion peak of anti-CD19-CAR T cells was 32.54 ± 19.94% on days 4–14 (median time was 11.31 ± 3.47 days) after the infusion. The mean level of anti-CD19-CAR T cells was 2.58 ± 1.32% when the patients developed aGVHD. (B) DNA level of anti-CD19-CAR gene showed the same trend.