DILI |
drug-induced liver injury |
CLD |
chronic liver disease |
HCC |
hepatocellular carcinoma |
NAFLD |
non-alcoholic fatty liver disease |
NASH |
non-alcoholic steatohepatitis |
NTBI |
non-transferrin bound iron |
ROS |
reactive oxygen species |
TAA |
thioacetamide |
AA |
allyl alcohol |
CCl4
|
carbon tetrachloride |
HE |
hematoxylin and eosin |
DAB |
3,3′-diaminobenzidine |
γH2A.X |
phospho-histone H2A.X |
PBS |
phosphate buffered saline |
MDA |
malondialdehyde |
TBARS |
thiobarbituric acid reacting substances |
GSSG |
glutathione-S-S-glutathione |
GSH |
glutathione-SH |
p-RIP3 |
phosphorylated-receptor-interacting protein kinase 3 |
GPX4 |
glutathione peroxidase 4 |
GAPDH |
glyceraldehyde-3-phosphate dehydrogenase |
RES |
reticuloendothelial system |
Nrf2 |
nuclear factor-erythroid 2-related factor 2 |
HO-1 |
heme oxygenase-1 |