Figure 2.

Nutrient chemosensors, ghrelin and ghrelin-processing enzymes relative mRNA expression in the corpus and antrum of a 12-week standard laboratory diet-fed (SLD, n = 5) or high-fat diet-fed (HFD, n = 5–7) mice. Relative mRNA expression of (a) ghrelin, the ghrelin-processing enzymes, (b) GOAT and (c) PC1/3, and the nutrient chemosensors for the detection of (d–f) fatty acids, (g–i) protein digestion products and (j) sweet and umami taste. The expression is relative to the average housekeeper values for PPIA, HPRT and B2M. Data are expressed as mean ± SEM. Differences in gene expression were determined by two-way ANOVA followed by Sidak post hoc test. Statistical significance for two-way ANOVA is defined as ** p < 0.01 and *** p < 0.001. Statistical significance for Sidak post hoc test is denoted as ^§ p < 0.01.