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. 2020 Aug 24;12(9):2561. doi: 10.3390/nu12092561

Figure 1.

Figure 1

Pathogenesis of SARS-CoV-2 and adjuvant actions of melatonin. We postulate that melatonin significantly suppresses the immune response, the enhanced inflammation, and the excessive oxidative stress, triggering a “cytokine storm”. The “cytokine storm” induces acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) accompanied by severe complications.