Table 2.
Total (N = 109) |
Mild (N = 22) |
Moderate (N = 34) |
Severe * (N = 53) |
p-Value | |
---|---|---|---|---|---|
Median age (SD)–yr | 58 ± 14 | 46 ± 16 | 60 ± 13 | 61 ± 12 | 0.001 |
Female sex–no. (%) | 44 (40) | 14 (64) | 20 (60) | 10 (19) | 0.001 |
Mean BMI–kg/m2 (SD) † | 27 ± 14 | 26 ± 5 | 26 ± 4 | 28 ± 5 | 0.287 |
Days of hospitalization | 9 ± 10 | 0 (0) | 5 ± 3 | 15 ± 10 | <0.001 |
25(OH)D nmol∙L−1 | 54 ± 25 | 64 ± 31 | 54 ± 19 | 50 ± 24 | 0.116 |
PTH–ng∙L−1 | 45 ± 18 | 35 ± 13 | 42 ± 14 | 50 ± 20 | 0.001 |
Calcium–mmol∙L−1 | |||||
total | 2.37 ± 0.09 | 2.37 ± 0.09 | 2.36 ± 0.09 | 2.39 ± 0.08 | 0.183 |
ionized | 1.22 ± 0.04 | 1.24 ± 0.03 | 1.22 ± 0.04 | 1.22 ± 0.04 | 0.310 |
Phosphate–mmol∙L−1 | 1.01 ± 0.17 | 1.02 ± 0.14 | 1.04 ± 0.16 | 0.99 ± 0.19 | 0.473 |
Creatinine–mg∙dL−1 | 0.87 ± 0.23 | 0.82 ± 0.15 | 0.80 ± 0.17 | 0.93 ± 0.27 | 0.017 |
Urea–mg∙dL−1 | 32 ± 11 | 28 ± 7 | 32 ± 9 | 33 ± 13 | 0.242 |
CRP–mg∙dL−1 | 0.29 ± 0.44 | 0.2 ± 0.28 | 0.2 ± 0.21 | 0.39 ± 0.56 | 0.067 |
IL-6–ng∙L−1 | 3.1 ±4.98 | 1.45 ± 2.06 | 1.96 ± 1.95 | 4.43 ± 6.6 | 0.041 |
D-dimer–ug∙L−1 | 807 ± 1591 | 607 ± 797 | 632 ± 633 | 1001 ± 2160 | 0.475 |
Ferritin–ug∙L−1 | 263 ± 230 | 139 ± 118 | 260 ± 183 | 317 ± 271 | 0.001 |
† BMI, body-mass index; the BMI is the weight kilograms divided by the square of the height in meters. * 35 patients received oxygen supply only, two patients were treated with non-invasive ventilation, and 16 with invasive ventilation. Disease severity was graded according to intensity of treatment: mild = ambulatory treatment; moderate = hospital treatment; severe = inward treatment with respiratory (oxygen) supply or treatment at the intensive care unit (ICU) with non-invasive or invasive ventilation; PTH = parathyroid hormone; CRP = C-reactive protein; IL-6 = interleukin 6; data are depicted as mean ± SD, p-values were calculated with Kruskal–Wallis Test.