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Position of the mutated residues on HducCdtB structure regarding DNA or lipid ligands. The HducCdtB catalytic domain is represented with two putative ligands, octameric DNA (a) or phosphatidylinositol-3,4-bisphosphate (b). H160: Yellow; D273: Purple; R117, R144, and N201: Orange; A163: Ochre; F156 and T158: Pink; G114: Red.
