Table 5.
Compound-dependent tandem mass spectrometry parameters for tetrodotoxin (TTX) and the screened analogues.
| Compounds | Precursor Ion (m/z) | Collision Energy (V) | Product Ion 1 (m/z) |
|---|---|---|---|
| TTX/4-epi-TTX | 320.1 | 23 | 302.1(Q) |
| 35 | 162.1 (q) | ||
| 5,6,11-trideoxy-TTX | 272.1 | 30 | 254.1 (Q) |
| 35 | 162.1 (q) | ||
| 11-norTTX-6(R/S)-ol | 290.1 | 30 | 272.1 (Q) |
| 35 | 162.1 (q) | ||
| 4,9-anhydro-TTX | 302.0 | 24 | 256.0 (Q) |
| 35 | 162.1 (q) | ||
| 5-deoxy-TTX/11-deoxy-TTX | 304.1 | 30 | 286.1 (Q) |
| 30 | 176.0 (q) | ||
| Arginine | 175.0 | 30 | 70.0 (Q) |
| 30 | 60.0 (q) | ||
| Hydroxy arginine | 191.0 | 30 | 86.0 (Q) |
| 30 | 68.0 (q) |
1 Q: Quantitative transition; q: qualifier transition.