Table 1.
Offspring body composition and blood pressure at 4 and 8 weeks of age.
| Experimental Group | Male | Female | ||||||
|---|---|---|---|---|---|---|---|---|
| High LA (18% Fat) |
High LA (36% Fat) |
Low LA (18% Fat) |
Low LA (36% Fat) |
High LA (18% Fat) |
High LA (36% Fat) |
Low LA (18% Fat) |
Low LA (36% Fat) |
|
| 4 Week Offspring | ||||||||
| Heart (% BW) | 0.49 ± 0.02 | 0.53 ± 0.02 | 0.50 ± 0.02 | 0.51 ± 0.02 | 0.52 ± 0.003 a | 0.55 ± 0.002 b | 0.51 ± 0.02 a | 0.53 ± 0.01 b |
| Lungs (% BW) | 1.05 ± 0.07 | 1.07 ± 0.10 | 1.02 ± 0.07 | 1.29 ± 0.06 | 1.39 ± 0.09 | 1.28 ± 0.12 | 1.20 ± 0.11 | 1.19 ± 0.08 |
| Kidney (%BW) | 1.08 ± 0.03 | 1.12 ± 0.03 | 1.10 ± 0.02 | 1.06 ± 0.01 | 1.02 ± 0.10 | 1.11 ± 0.02 | 1.13 ± 0.04 | 1.05± 0.02 |
| Liver (% BW) | 5.05 ± 0.15 | 4.92 ± 0.13 | 5.05 ± 0.12 | 4.71 ± 0.10 | 4.98 ± 0.07 a | 4.73 ± 0.08 b | 4.76 ± 0.16 a | 4.60 ± 0.11 b |
| Gonadal fat (%BW) * | 0.49 ± 0.03 | 0.52 ± 0.04 | 0.56 ± 0.03 | 0.39 ± 0.03 | 0.64 ± 0.09 | 0.66 ± 0.05 | 0.79 ± 0.05 | 0.54 ± 0.04 |
| Retroperitoneal fat (%BW) | 0.57 ± 0.06 | 0.52 ± 0.04 | 0.52 ± 0.07 | 0.47 ± 0.05 | 0.42 ± 0.06 | 0.37 ± 0.03 | 0.42 ± 0.03 | 0.34 ± 0.03 |
| Systolic BP (mmHg) | 86.2 ± 4.0 | 92.6 ± 4.6 | 89.0 ± 5.9 | 91.9 ± 3.8 | 85.8 ± 7.2 | 87.4 ± 3.3 | 91.8 ± 4.1 | 91.3 ± 5.2 |
| Diastolic BP (mmHg) | 65.5 ± 3.6 | 68.2 ± 3.7 | 65.4 ± 4.6 | 68.3 ± 3.3 | 61.9 ± 7.1 | 61.1 ± 2.1 | 68.9 ± 4.1 | 64.5 ± 2.2 |
| 8 Week Offspring | ||||||||
| Brain (%BW) | 0.56 ± 0.02 | 0.57 ± 0.02 | 0.55 ± 0.02 | 0.57 ± 0.01 | 0.80 ± 0.01 | 0.84 ± 0.02 | 0.79 ± 0.01 | 0.79 ± 0.03 |
| Heart (% BW) | 0.34 ± 0.01 | 0.37 ± 0.01 | 0.36 ± 0.01 | 0.38 ± 0.01 | 0.39 ± 0.01 | 0.40 ± 0.01 | 0.39 ± 0.02 | 0.40 ± 0.01 |
| Lungs (% BW) | 0.61 ± 0.06 | 0.62 ± 0.05 | 0.61 ± 0.05 | 0.63 ± 0.04 | 0.66 ± 0.04 | 0.68 ± 0.04 | 0.60 ± 0.02 | 0.68 ± 0.05 |
| Kidney (%BW) | 0.83 ± 0.04 | 0.83 ± 0.02 | 0.84 ± 0.02 | 0.88 ± 0.03 | 0.88 ± 0.03 | 0.87 ± 0.03 | 0.85 ± 0.03 | 0.81 ± 0.02 |
| Liver (% BW) | 4.80 ± 0.08 | 5.00 ± 0.14 | 4.96 ± 0.09 | 5.00 ± 0.08 | 4.49 ± 0.16 | 4.63 ± 0.08 | 4.43 ± 0.10 | 4.56 ± 0.08 |
| Gonadal fat (%BW) | 1.30 ± 0.10 | 1.25 ± 0.08 | 1.34 ± 0.08 | 1.19 ± 0.09 | 1.38 ± 0.15 | 1.56 ± 0.07 | 1.53 ± 0.19 | 1.57 ± 0.23 |
| Retroperitoneal fat (%BW) | 1.22 ± 0.09 | 1.29 ± 0.11 | 1.32 ± 0.11 | 1.16 ± 0.10 | 0.88 ± 0.10 | 0.94 ± 0.11 | 0.94 ± 0.09 | 0.86 ± 0.08 |
| Systolic BP (mmHg) | 116.0 ± 5.0 | 109.1 ± 5.2 | 113.4 ± 3.4 | 105.8 ± 6.6 | 122.7 ± 10.1 a | 103.2 ± 3.0 b | 120.4 ± 8.2 a | 107.4 ± 5.9 b |
| Diastolic BP (mmHg) | 82.9 ± 0.2 | 73.5 ± 5.3 | 80.3 ± 3.3 | 74.4 ± 5.7 | 82.3 ± 5.1 | 71.8 ± 2.3 | 86.0 ± 7.1 | 74.5 ± 6.3 |
All values are mean ± SEM and organ weights are expressed as a percentage of bodyweight (%BW). A two-way ANOVA was used to analyse results with maternal dietary fatty acid ratio and maternal dietary fat content as factors, all comparisons are made within sex groups. Different superscripts (a, b) denote values which are significantly different (p < 0.05). * indicates a significant interaction effect of maternal dietary fatty acid ratio and maternal fat content on gonadal fat weight in male (p < 0.01) and female (p < 0.05) offspring. n = 6–9 per dietary group.