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. 2020 Aug 26;12(9):547. doi: 10.3390/toxins12090547

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Profiling of immuno-related genes in the adenine-induced damaged kidney of mice under GF and SPF conditions. (a) Transcriptional profiling of immuno-related genes in the kidneys of the four mice groups: SPF + ND, SPF + AD, GF + ND, and GF + AD (in the experiment described in Figure 3a). (b) Scatter plot comparing expression levels of SPF + AD and GF + AD groups. (c) Expression level of Il17a mRNA in the kidney. (d) Plasma IL-17 levels. (e) Expression levels of Il17f, Il23, and Foxp3 mRNA in the kidney. * p < 0.05, ** p < 0.01 compared between indicated groups (ANOVA).