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Experimental set up (A) and timeline (B) of the employed ex vivo colon continuous fermentation model. The gut microbiota was propagated in the inoculating reactor (IR) for 15 days before seeding three sub-reactors (CR no treatment control, ER1 with microcrystalline cellulose control, and ER2 with test sample). M; Nutritive medium, g; pH and dissolved oxygen sensors, W; waste, F; percentage of the medium input (green lines) or inoculum input (red lines).
