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. 2020 Sep 1;12(9):2669. doi: 10.3390/nu12092669

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The test formulation modulates gut microbiota composition. (A–C) Histograms of the linear discriminant analysis (LDA) scores showing microbial taxa that vary significantly in abundance between: (A) no-treatment control and test treatment, (B) microcrystalline cellulose control and test treatment, (C) no-treatment control and microcrystalline cellulose treatment. (C,D) Relative abundance charts for target species: (D) relative abundance of inoculated probiotic, B. coagulans, over 48 h with test treatment; (E) relative abundance of F. prausnitzii over 48 h with no-treatment control, microcrystalline cellulose control treatment and test treatment. Triangle symbols indicate donor 1 samples and circles for donor 2 samples.