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Sphingosine-1-phosphate (S1P) distribution in lipoprotein fractions. Sphingosine-1-phosphate (S1P) concentration in lipoprotein fractions collected from Npc1l1WT or Npc1l1KO male mice (initially 8–10 weeks old) fed a Western diet (WD) for the indicated periods in the absence (−) or presence (+) of ezetimibe (Eze). Representative lipoprotein profiles from two independent experiments with two mice in each group are shown.
