Effects of Pt-PS on the composition of the gut microbiota in HFD mice (n = 5). Univariate differential abundance of operational taxonomic units (OTUs) at the phylum level was tested by combining Fisher’s exact test and false discovery rate (FDR) to compare control, HFD, Sb-PS, and Pt-PS groups and mouse genotypes; p values were corrected with the Benjamini–Hochberg method to correct for the false discovery rate across multiple comparisons, which were generated using Metastats and considered significant for p < 0.05. The difference between control and HFD mice, HFD and Pt-egg oil groups was analyzed using Student’s test. (a) Chao index of OTU level; (b) Shannon index of OTU level; (c) Simpson index of OTU level; (d) hierarchical clustering tree at the OTU level; (e) Principal Coordinates Analysis (PCoA) at the OTU level. * p < 0.05, ** p < 0.01 *** p < 0.001 vs. HFD.