Table 2.

Nuclear Magnetic Resonance NMR Spectroscopic Data (500 MHz, dimethyl sulfoxide-d₆ DMSO-d₆) for aeruginosamide AEG371 (Dma-Phe-Phe-Pro-Pyr-Tzl-COOMe).

Residue	Position	äC, Type	äH (J in Hz)	ROESY a	HMBC b
Tzl-COOMe	1	51.1, CH3	3.81, s	4	2
	2	160.3, C
	3	144.5, C
	4	128.0, CH	8.43, s	1	2, 5
	5	173.4, C
Pyr	6	57.5, CH	5.32, dd (8.2, 2.4)		5
	7	30.5, CH2	2.05, m
			2.27, m
	8	23.3, CH2	1.87, m
			1.96, m
	9	45.9, CH2	3.70, m	11
Pro	10	169.7, C
	11	56.7, CH	4.68, brs	9	10
	12	27.1, CH2	1.81, m
			2.20, m
	13	23.7, CH2	2.04, m
	14	46.0, CH2	3.50, m	16
			3.66, m
Phe	15	168.2, C
	16	50.0, CH	4.77, brs	14	15, 18
	17	36.1, CH2	2.76, dd (14.1, 8.8)	19	15, 16, 18
			2.97, dd (14.1, 4.3)
	18	136.3, C
	19	128.6, CH	7.11, d (7.1)	17
	20	127.1, CH	7.23, m
	21	125.3, CH	7.18, m
	NH(1)		8.18, d (8.9)	23	22
Phe	22	173.3, C
	23	57.1, CH	3.03, dd (9.0, 4.2)	30, NH(1)	29
	24	39.6, CH2	2.35, dd (13.3, 9.0)	26	22, 23, 25
			2.67, dd (13.3, 4.1)
	25	137.4, C
	26	128.6, CH	7.11, d (7.1)	24
	27	127.1, CH	7.23, m
	28	125.4, CH	7.18, m
	NH(2)
Dma c	29	53.2, C
	30	24.7, CH3	0.79, s	23
	31	26.6, CH3	0.76, s	32
	32	144.9, CH	5.26, dd (17.5, 10.7)	31	29, 31
	33	110.9, CH2	4.72, m

^a ROESY Rotation Frame Nuclear Overhauser Effect Spectroscopy; ^b HMBC correlations are given from proton(s) stated to the indicated carbon atom; ^c Dma: 1,1-dimethylallyl.