Figure 4.
Comparison of the electron density maps of the RNP of RABV (EMD-4995) and VSV (EMD-1663). The viewing direction is indicated above each panel, where: (A) a view from the side, (B) a view from the membrane and (C) a view towards the RNA binding groove. The distance between the helical turns, as well as the deviation of the helical turns from the central axis of the virion, are indicated. The location of the genome is indicated by a black dot or a black dotted line. The N-protein structures (pdb 2gtt (RABV), 2gic (VSV)) are docked in the corresponding densities and shown in purple. The VSV M-protein structures (2w2r, blue) are docked in the orientation, as proposed by [4], whilst the location, but not the orientation, of the RABV M-protein C-terminal domain is depicted as a blue density. The proposed location of the M-protein N-terminus is indicated by red stars. Dashed lines in the middle panel indicate the step to the corresponding M-protein on the next helical turn.