Table 7.
Docking scores for T47, T1J, and T7D derivatives having hydrogen acceptors and donor atoms.
| Compound | Highest Docking Score −log10(Kd) |
Compound | Highest Docking Score −log10(Kd) |
|---|---|---|---|
| KF08 | 8.80 | JN16 | 8.16 |
| KF03 | 8.07 | JMH5 | 7.42 |
| KF04 | 7.14 | JN14 | 6.00 |
| KF07 | 6.90 | JCN6 | 5.82 |
| KF01 | 6.77 | JCN8 | 5.79 |
| KF02 | 6.66 | JN12 | 5.61 |
| GN06 | 6.41 | JN10 | 5.28 |
| T1J | 5.92 | T7DM | 3.77 |
| GN07 | 5.67 | T7D | 3.47 |
| GM09 | 5.61 | ||
| KF05 | 5.52 | ||
| EW13 | 7.33 | HS06 | 7.85 |
| EW14 | 7.32 | HS05 | 7.03 |
| EW11 | 6.99 | T47 | 4.69 |
Bolded compounds are the parent compounds and are shown for comparison.