Table 5.
Vaccine Group | Geomean HI Antibody Titers | Mean Lung Virus Titers (log10 TCID50/g) |
---|---|---|
PBS-PBS-PBS | 5.0 | 6.14 |
NC95-PBS-PBS | 5.0 | 3.44 |
NC95-G08-G08 | 26.4 | 1.25 |
NC95-PA10-PA10 | 242.5 | 0.85 |
NC95-G08-PA10 | 40.0 | 1.82 |
NC95-PA10-G08 | 160.0 | 0.85 |
HI antibody titers were determined at the time of challenge, while virus titers were determined 3 days post challenge. Correlation between titers was determined using the Spearman correlation coefficient (r = −0.91).