Table 2.
Summary of host and viral integration sites.
| Breakpoints in the Human Genome | ||
|---|---|---|
| Chromosome | Number of Sites | Genes Associated |
| 1 | 14 | PLA2G4A, RABGAP1L, MCOLN2, CASZ1 (I#1) |
| 2 | 6 | SF3B1 (I#1) |
| 3 | 7 | PTPRG (I#1), ATP11B, EEFSEC, ADAMTS9 (I) |
| 4 | 6 | SRD5A2L2, KCNIP4, RELL1, GRID2, FRG1(I), |
| 5 | 21 | TLX3, XRCC4, ISL1, PRLR, CAMK2A(I), CD74(I) |
| 6 | 15 | IL20RA, GMDS, MAP3K7IP2, CDKAL1 (I#4), MRDS1 (I#6), CDKAL1, RP3348–I23.2 |
| 7 | 5 | |
| 8 | 6 | MYC |
| 9 | 8 | DENND1A;mir601, INPP5E (I) |
| 10 | 3 | |
| 11 | 8 | PARVA;TEAD1, LUZP2 (I#10;Tr#1), TTC9C (E#1), AHNAK (I) |
| 12 | 3 | AX747640, BEST3 (I#4;Tr#1), KMT2D (I#34) |
| 13 | 1 | DACH1 (I) |
| 14 | 1 | NOVA1 |
| 15 | 3 | ATPBD4;XP_002343377 |
| 16 | 5 | |
| 17 | 1 | DCAF7 (I#3) |
| 18 | 2 | CDH2 |
| 19 | 4 | EVI5L, ECH1, GRWD1 |
| 20 | 3 | SNTA1, CBFA2T2, BCL2L1 (E), TPX2 (I) |
| Y | 1 | |
| Total | 123 | |
| Breakpoints in the Viral Genome | ||
| Genomic Region | Number of Sites | Gene |
| Large T Antigen | 42 | LT |
| Small T Antigen | 4 | ST |
| NCCR | 8 | |
| Viral Capsid Protein 1 | 23 | VP1 |
| Viral Capsid Protein 2 | 10 | VP2 |
| Between LT and VP1 | 2 | |
| Total | 89 | |
In brackets: I stands for Intron, Tr for Transcript, and E for Exon. The number following # is the corresponding Intron/Transcript/Exon number of the gene.