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. 2020 Sep 3;12(9):977. doi: 10.3390/v12090977

Figure 2.

Figure 2

Schematic of Signal Transducer and Activator of Transcription (STAT) protein domain architecture and the biological defects and phenotypes observed in STAT family member knockout (KO) mice. IL, interleukin; IFN, interferon; EPO, erythropoietin; GM-CSF, granulocyte macrophage colony stimulating factor; N, N-terminal domain; CC, coiled coil domain; DBD, DNA-binding domain; LD, linker domain; SH2, Src Homology 2; TA, Transactivation domain [90,91,92,93,94,95,96,97]. Figure created using BioRENDER.com.