Table 1.
Interrater reliability of overall MGS scores.
| Total MGS Scores 1 | Mean MGS Scores 1 | Mean MGS Difference Scores 2 | |
|---|---|---|---|
| Interrater Reliability between All Scorers | |||
| ICC over all time points 3 | 0.851 | 0.845 | 0.855 |
| ICC at baseline | 0.556 | 0.522 | - |
| ICC at 150 min after anesthesia | 0.799 | 0.802 | 0.813 |
| ICC on day 2 after anesthesia | 0.329 | 0.317 | 0.433 |
| Interrater Reliability between Inexperienced Scorers | |||
| ICC over all time points 3 | 0.749 | 0.757 | 0.736 |
| Interrater Reliability between Experienced Scorers | |||
| ICC over all time points 3 | 0.824 | 0.821 | 0.811 |
| Interrater Reliability between Three Scorers, Excluding One Person at a Time | |||
| ICC over all time points 3, excluding scorer #1 (inexperienced) | 0.812 | 0.797 | 0.791 |
| ICC over all time points 3, excluding scorer #2 (inexperienced) | 0.826 | 0.822 | 0.855 |
| ICC over all time points 3, excluding scorer #3 (experienced) | 0.814 | 0.808 | 0.816 |
| ICC over all time points 3, excluding scorer #4 (experienced) | 0.791 | 0.786 | 0.799 |
1 Scores obtained at baseline, 150 min, and two days after anesthesia. 2 Scores obtained at 150 min, and two days after anesthesia. Baseline scores were subtracted from the score generated after anesthesia. 3 Three scores of each mouse were included in the analysis (i.e., one score each was obtained from images generated at baseline, 150 min, and two days after anesthesia). Abbreviations: Intraclass correlation (ICC), Mouse Grimace Scale (MGS).