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. 2020 Oct 12;6:39. doi: 10.1038/s41522-020-00146-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a HPV vaccination status in all the samples showed a decreased trend in vaccination coverage as age increased. b HPV prevalence and oncogenic HPV prevalence in all samples according to age. An overall high HPV prevalence was observed between age of 18–26. Most of the HPV infection contained oncogenic HPV in all the age groups. c Microbial alpha diversity based on Shannon index of all the samples showed no significant difference among age groups (Kruskal–Wallis test; p > 0.05). d Microbial alpha diversity based on Shannon index of all the samples did not show significant difference between the groups with and without vaccination (Wilcoxon rank-sum one-sided test; p > 0.05). Data were presented as mean values with standard deviations.