Table 1.

The risk of human papillomavirus (HPV) by different characteristics.

	Unadjusted OR (95% CI)			Adjusted OR (95% CI)			Adjusted OR (95% CI)
	HPV+	Oncogenic HPV	Non-oncogenic HPV	HPV+	Oncogenic HPV	Non-oncogenic HPV	Multiple HPV	Multiple oncogenic HPV
Age
14–18 years	Reference	Reference	Reference	Reference	Reference	Reference	Reference	Reference
19–24 years	2.7 (1.4–5.4)a	2.5 (1.2–5.1)a	3.0 (1.1–8.2)a	4.0 (1.9-8.7)a	3.2 (1.5–6.8)a	3.3 (1.2–9.2)a	4.1 (1.7–9.7)a	3.7 (1.5–9.3)a
25–29 years	0.7 (0.3–1.5)	0.6 (0.3–1.5)	0.1 (0.0–1.2)	2.2 (0.6–7.6)	1.8 (0.5–6.4)	0.3 (0.0–3.1)	2.2 (0.4–12.4)	1.7 (0.3-11.1)
HPV vaccination
No	Reference	Reference	Reference	Reference	Reference	Reference	Reference	Reference
Yes	1.0 (0.5–1.7)	0.9 (0.5–1.5)	1.0 (0.5–2.0)	0.5 (0.2–1.1)	0.5 (0.2–1.00)a	0.5 (0.2–1.0)	0.3 (0.1–0.9)a	0.4 (0.1–1.0)a
Sample source
Screening cohort	Reference	Reference	Reference	Reference	Reference	Reference	Reference	Reference
Youth clinic	4.0 (2.3–6.9)a	4.5 (2.5–7.9)a	6.4 (2.4–16.8)a	5.4 (2.4–12.2)a	5.5 (2.4–12.6)a	3.7 (1.3–11.2)a	16.1 (4.9–53.3)a	17.4 (4.6–65.6)a
Vaginal microbiota
L. crispatus	Reference	Reference	Reference	Reference	Reference	Reference	Reference	Reference
L. iners	0.9 (0.5–1.6)	1.3 (0.7–2.4)	1.00 (0.4–2.3)	0.7 (0.3–1.3)	1.0 (0.5–2.1)	0.8 (0.3–1.9)	0.8 (0.3–1.8)	1.0 (0.4–2.3)
Other Lactobacilli	1.9 (0.4–8.1)	0.4 (0.1–2.2)	1.6 (0.3–8.4)	2.1 (0.5–10.2)	0.4 (0.1–2.2)	1.4 (0.2–8.4)	2.2 (0.3–16.8)	0.7 (0.1–4.8)
Non-Lactobacillus dominated	2.0 (1.1–3.7)a	2.1 (1.2–4.0)a	2.2 (1.1–4.8)a	1.7 (0.9–3.5)	2.0 (1.0–3.9)a	2.0 (0.9–4.6)	2.5 (1.1–5.9)a	2.4 (1.0–5.8)a

All the data is presented as odds ratios (OR) and 95% confidence intervals (CI) calculated by multivariable logistic regression. The risk of (any subgroup of) HPV infection was compared to group of “HPV–” in all analyses (see raw number in supplementary Table 3).

^aStatistically significant difference (<0.05).