Table 3.

Differential expression of receptors in mice bearing HT-116 subcutaneous cancer after treatment with 5-FU and 5FU-SLN₄ and staining scores analysis.

	Control	5-FU	5FU-SLN4	p-value (5-FU versus 5FU-SLN4)	Significant?
EGFR
% Positive cells	76.1 ± 2.2	69.1 ± 4.1	71.4 ± 2.8	0.467	No
% Weak positive cells	45.1 ± 3.2	46.9 ± 2.5	33.4 ± 2.6
% Moderate positive cells	24.9 ± 4.2	18.9 ± 0.2	27.3 ± 1.8
% Strong positive cells	6.1 ± 0.9	3.3 ± 0.5	10.7 ± 0.5
% Negative cells	23.9 ± 4.1	30.9 ± 1.7	28.6 ± 4.7
H score	113.4	94.6	119.8
HER2
% Positive cells	80.5 ± 2.8	26.9 ± 1.4	3.7 ± 0.5	0.0001	Yes
% Weak positive cells	0.001	26.8 ± 3.6	3.6 ± 0.2
% Moderate positive cells	10.1 ± 2.2	0.1 ± 0.002	0.02 ± 0.0
% Strong positive cells	70.4 ± 2.8	0.006 ± 0.0	0.003 ± 0.0
% Negative cells	20.4 ± 1.8	73.1 ± 8.6	96.3 ± 1.7
H score	57.9	27.1	3.7
VEGF
% Positive cells	20.5 ± 4.2	1.27 ± 0.05	2.8 ± 0.4	0.001	Yes
% Weak positive cells	11.7 ± 3.2	1.23 ± 0.01	1.8 ± 0.02
% Moderate positive cells	7.1 ± 1.6	0.04 ± 0.0	0.7 ± 0.04
% Strong positive cells	1.8 ± 0.2	0.0003 ± 0	0.25 ± 0.001
% Negative cells	79.5 ± 5.1	99.1 ± 1.4	97.2 ± 3.6
H score	31.3	0.91	4.1