. 2020 Oct 12;15:283. doi: 10.1186/s13023-020-01527-0

Table 2.

BMI, percentage of body fat, and endocrine data of early treated (before 1st birthday; group A) and later treated (after 1st birthday; group B) patients at all observational time points are shown. ^aindicates a difference between the groups at the significance level of 0.05

Age	1 ± 0.25 yrs		2 ± 0.25 yrs		3 ± 0.5 yrs		4 ± 0.5 yrs		5 ± 0.5 yrs
Group	A (n = 21)	B (n = 32)	A (n = 21)	B (n = 41)	A (n = 21)	B (n = 41)	A (n = 20)	B (n = 41)	A (n = 11)	B (n = 39)
mean ± SD
BMI_nonPWS-SDS	−1.73 ± 1.41	−0.99 ± 1.32	−1.04 ± 1.20	−0.88 ± 1.20	−0.16 ± 1.10	−0.62 ± 1.49	0.15 ± 1.16	0.02 ± 1.36	0.22 ± 0.92	0.18 ± 1.18
BMI_PWS-SDS	−0.49 ± 0.74	0.11 ± 0.77	−0.68 ± 0.69	−0.61 ± 0.71	−0.85 ± 0.77	−1.10 ± 0.86	−1.01 ± 0.81	−1.12 ± 0.95	−1.26 ± 0.64	−1.30 ± 0.82
% body fat					14.74 ± 6.24	15.06 ± 5.54	17.52 ± 8.59	19.41 ± 6.57	19.42 ± 5.32	21.10 ± 4.80
IGF-I SDS	−0.62 ± 1.62	−0.57 ± 1.69	−0.30 ± 2.02	0.32 ± 2.53	−0.86 ± 2.21	−0.57 ± 2.07	−0.74 ± 1.78	−0.47 ± 1.97	−0.35 ± 2.45	−0.98 ± 1.25
IGFBP-3 SDS	0.25 ± 0.71^a	−0.79 ± 0.69^a	1.22 ± 0.76^a	0.58 ± 0.96^a	1.31 ± 0.78^a	0.89 ± 0.91^a	1.46 ± 1.03^a	0.99 ± 0.81^a	1.12 ± 1.19^a	0.97 ± 0.91^a