Table 4.

Association between MIF rs5844572 and CDKN2A methylation

	Genotype (repeat number)						X/X vs. X/7 + 7/7	X/X + X/7 vs. 7/7
	5/5	5/6	5/7	6/6	6/7	7/7	adjusted OR* (95% CI); p value	adjusted OR* (95% CI); p value
p14-UM (105)	13	40	16	19	14	3	reference	reference
p14-M (54)	3	17	12	9	9	4	1.77 (0.864–3.63); p = 0.12	4.51 (0.79–25.7); p = 0.090
p16-UM (89)	9	31	12	23	12	2	reference	reference
p16-M (70)	7	26	16	5	11	5	2.57 (1.26–5.24); p = 0.0094	5.51 (0.90–33.9); p = 0.066

*by logistic regression analysis after adjustment for age, gender, clinical type and disease extension

UM Unmethylated, M Methylated, X: 5 or 6 repeat allele; 7: 7 repeat allele