Fig. 6.

Changes in weight, fat, insulin, leptin and metabolic activity of germ-free mice receiving FMT from adult or aged mice. a Feces from adult (n = 8) and aging (n = 5) WT FVB/N mice were transplanted into 8-week-old germ-free mice through oral gavage. b Beta-diversity using Principal Coordinate Analysis (PCoA) of Jaccard distances (p = 0.057). Graphs show changes in the percentage of fat between days 0 and 10 days post transplant (c). Food consumption (d), and average respiratory quotient (RQ) (e) were measured from days 2–10. Insulin (f) and leptin (g) were measured in the blood on day 10. *p < 0.05, **p < 0.01, and ***p < 0.001