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. 2020 Aug 6;7(3):88. doi: 10.3390/bioengineering7030088

Table 2.

WNT pathway target genes and the effect of each on the cell.

Gene Effect
RUNX2 osteogenic differentiation
RANKL Recruitment of osteoblast-like cell precursors
OPG regulates bone turnover, blocks RANKL
VCAN cell proliferation and migration