. Author manuscript; available in PMC: 2020 Oct 13.

Published in final edited form as: Anticancer Res. 2019 Sep;39(9):4877–4884. doi: 10.21873/anticanres.13673

Table III.

Hazard ratios for colorectal cancer according to aspirin use status, stratified by colorectal cancer risk factors.

Risk strata	Aspirin use	HR_adj (95%CI)	p-Value
All participants	No	Reference^*	--
	Yes	0.77 (0.65, 0.90)	0.001
Low/normal CVD-risk	No	Reference^†	--
	Yes	0.72 (0.54, 0.96)	0.025
High CVD-risk	No	Reference^†	--
	Yes	0.79 (0.65, 0.96)	0.017
No family history of CRC	No	Reference^‡	--
	Yes	0.72 (0.60, 0.86)	<0.001
Family history of CRC	No	Reference^‡	--
	Yes	0.97 (0.70, 1.36)	0.882
History of colonoscopy without polypectomy	No	Reference^#	--
	Yes	0.90 (0.70, 1.15)	0.398
History of colonoscopy with polypectomy	No	Reference^#	--
	Yes	0.52 (0.29, 0.93)	0.028

HR: Hazard ratio; CI: confidence Interval; CVD: cardiovascular disease; CRC: colorectal cancer.

Adjusted for age, CVD risk, family history of CRC, and history of polypectomy

^†

Adjusted for age, family history, and history of polypectomy

^‡

Adjusted for age, CVD risk, and history of polypectomy

Adjusted for age, CVD risk, and family history of CRC.