Table 1.
Overview of criteria and nomenclature used in literature to define HRSV genotypes.
| Reference | Genotyping region | Genotyping definitions | Genotype nomenclature | Genotypes identified HRSV-A | Genotypes identified HRSV-B |
|---|---|---|---|---|---|
| Peret et al. (1998) | HVR2 | BS ≥ 78% | Gene + subtype + number | GA1–GA5 | GB1–GB4 |
| Peret et al. (2000) | HVR2 | BS ≥ 70% | Gene + subtype + number | GA6–GA7 | / |
| Choi and Lee (2000) | G gene (HRSV-A) or partial HVR2 (HRSV-B) | Restriction analysis G gene | Gene + P + subtype + number | GP-A1–GP-A24 | GP-B1–GP-B6 |
| Venter et al. (2001) | HVR2 | BS ≥70%, p distance <0.07 | Country + subtype + number | SAA1 | SAB1–SAB3 |
| Trento et al. (2003) | G gene | / | / | / | No genotype, but “BA viruses” with 60 nt duplication |
| Zlateva et al. (2004) | Ectodomain | BS > 77% | Country + subtype + number | BE/A1 | / |
| Zlateva et al. (2005) | Ectodomain | BS > 77% | Gene + subtype + number | / | GB5–GB13 |
| Blanc et al. (2005) | HVR2 | BS ≥ 70%, p distance <0.07 | Country + subtype + number | / | URU1–URU2 |
| Trento et al. (2006) | HVR2 | BS ≥ 70% | City | / | BA (subclades I–VI) |
| Shobugawa et al. (2009) | HVR2 | BS ≥ 70%, p distance | City + subtype + number | NA1–NA2 | / |
| Dapat et al. (2010) | HVR2 | BS > 50% | Clustering + number | / | BA7–BA10 |
| Arnott et al. (2011) | HVR2 | BS ≥ 70%, p distance <0.07 | Clustering + number | / | SAB4 |
| Baek et al. (2012) | G gene | BS ≥ 70%, p distance <0.07 | City + subtype or clustering | CB-A | CB-B, BA11 |
| Eshaghi et al. (2012) | HVR2 | BS ≥ 70%, p distance <0.07 | City + number | ON1 | / |
| Cui et al. (2013) | HVR2 | BS ≥ 70%, p distance <0.07 | Clustering or unsystematic (CB-1) | NA3–NA4 | BA-C, CB-1 |
| Khor et al. (2013) | HVR2 | / | Clustering + number | / | BA12 cluster in BA genotype |
| Agoti et al. (2014) | G gene | For clades: BS ≥ 60%, average genetic distance cutoff 1.5% | Genotype of origin | / | BA1–BA12 → BA, subclades BA 2.1–2.4 |
| Liu et al. (2014) | HVR2 | BS > 85% | Clustering + number | / | BA1–BA10 |
| Trento et al. (2015) | G gene | p distance < 0.049 | Gene + subtype + number | NA1, NA2, NA4, ON1 → GA2 | / |
| Agoti et al. (2015b) | Ectodomain | Cluster identity threshold | Clustering + number | SAB1 variants V1–V10 | BA variants V1–V36 |
| Gimferrer et al. (2016) | HVR2 | BS ≥ 70%, p distance <0.07 | Clustering + number | / | BA13 |