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. 2020 Oct 12;10(10):e038798. doi: 10.1136/bmjopen-2020-038798

Table 1.

Primary tumour characteristics

n (%)
Tumour size
 T1 20 (32.8)
 T2 33 (54.1)
 T3 7 (11.5)
 T4 1 (1.6)
Nodal status
 N0 16 (26.2)
 N1 22 (36.1)
 N2 15 (24.6)
 N3 8 (13.1)
Histopathology
 Ductal 47 (77.0)
 Lobular 11 (18.0)
 Other 3 (4.9)
Histopathological grade
 Grade 1 0 (0)
 Grade 2 25 (41.0)
 Grade 3 34 (55.7)
 Unknown 2 (3.3)
ER expression
 Negative (0%) 14 (23.0)
 Weak (1%–9%) 2 (3.3)
 Moderate (10%–59%) 6 (9.8)
 High (>59%) 39 (63.9)
PR expression
 Negative (0%) 22 (36.1)
 Weak (1%–9%) 5 (8.2)
 Moderate (10%–59%) 5 (8.2)
 High (>59%) 29 (47.5)
HER2 status
 HER2-negative 52 (85.2)
 HER2-positive (CISH) 9 (14.8)
Ki-67 expression
 Negative (<5%) 2 (3.3)
 Weak (5%–14%) 15 (24.6)
 Moderate (15%–30%) 20 (32.8)
 High (>30%) 24 (39.3)
Focality
 Unifocal 50 (82.1)
 Multifocal 11 (18.0)
Subtype
 Luminal A-like 13 (21.3)
 Luminal B-like (HER2-negative) 29 (47.5)
 Luminal B-like (HER2-positive) 5 (8.2)
 HER2-positive, non-luminal 3 (4.9)
 Triple-negative 10 (16.4)
 Unknown 1 (1.6)
The first site of the distant metastasis
 Bone only 17 (27.9)
 Lung only 9 (14.8)
 Liver only 5 (8.2)
 Other 6 (9.6)
 Multiple sites 24 (39.3)

CISH, chromogenic in situ hybridisation; ER, oestrogen receptor; HER2, human epidermal growth factor receptor 2; PR, progesterone receptor.