Table 2.

Most common treatment-related adverse events in oncolytic virus clinical trials

Adverse event	Low grade (1–2)	High grade (3–4)	Total
Fever	56	4	60
Chills/rigors	40	0	40
Nausea/vomiting	30	8	38
Flu-like symptoms	27	2	29
Fatigue	36	4	40
Injection site pain	15	0	15
Other pain	19	7	26

*Number of studies reporting the listed event