Figure 8. Effect of RU486 on the growth of the SK-N-SH cell-derived neuroblastoma xenograft in nude mice. A, Nude mice implanted with fragments of the SK-N-SH cell derived-tumors (1 mm2) were treated with RU486 (15 mg/kg, two treatments/week) from day 1 to day 20 (horizontal gray band) and sacrificed on day 29. The results represent the mean of three independent experiments done in triplicate. Hematoxylin-eosin staining of 10-μm sections of control (B) or RU486-treated (C) xenografted tumors (magnification bar: 50 μm). Data are reported as means±SD. *P<0.05 vs vehicle (ANOVA).
