Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct;6(5):a005678. doi: 10.1101/mcs.a005678

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Takahashi et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial License, which permits reuse and redistribution, except for commercial purposes, provided that the original author and source are credited.

PMC Copyright notice

Figure 4. — Schema of JAK1 function impacting mutations leading to immunotherapy resistance. (JAK) Janus kinase, (PD-L1) programmed death-ligand 1, (PARPi) Poly (ADP-ribose) polymerase inhibition, (dMMR) mismatch repair deficiency, (IO) immune checkpoint blockade, (mt) mutant, (TILs) tumor infiltrating lymphocytes, (ISGs) interferon stimulated genes.