Table 3.
Participant Characteristics Associated With Best Corrected Visual Acuity (BCVA)
| N | BCVA Letter Score Median (Q1, Q3) | Univariable Analysis P Value | Multivariable Analysis P Value | |
| All | 127 | 80 (75, 85) | ||
| Clinical diagnosis | 0.03 | 0.09 | ||
| USH2 | 80 | 79 (74, 85) | ||
| ARRP | 47 | 82 (77, 87) | ||
| Age at enrollment , y | <0.001a | 0.04 | ||
| <30 y | 30 | 82 (77, 89) | ||
| 30 to < 40 y | 34 | 80 (76, 84) | ||
| 40 to < 50 y | 37 | 82 (77, 85) | ||
| ≥50 y | 26 | 72 (64, 79) | ||
| Gender | 0.09 | 0.01 | ||
| Female | 68 | 80 (73, 84) | ||
| Male | 59 | 80 (75, 86) | ||
| Duration of disease , yb | <0.001a | 0.004a | ||
| <10 | 37 | 83 (77, 87) | ||
| 10 to < 20 | 46 | 81 (76, 86) | ||
| ≥20 | 43 | 75 (66, 82) | ||
| Race/ethnicity | 0.44 | NAc | ||
| Non-Hispanic white | 113 | 80 (75, 85) | ||
| Other | 14 | 80 (75, 81) | ||
| Smoking status | 0.33 | NAc | ||
| Ever smoked daily | 33 | 82 (77, 84) | ||
| Never smoked daily | 94 | 79 (74, 85) | ||
| Dietary supplement use | 0.59 | NAc | ||
| None | 53 | 82 (75, 86) | ||
| Vitamin A only | 11 | 78 (74, 82) | ||
| DHA only | 5 | 77 (76, 80) | ||
| Lutein only | 9 | 79 (76, 84) | ||
| Multiple supplements | 49 | 79 (72, 85) |
a
Variable was analyzed as continuous.
b
One participant in the ARRP group was missing age of onset (a participant-reported field based on their awareness of visual symptoms) and duration of disease (computed based on age of onset and date of enrollment).
c
Factors with P values > 0.05 in the stepwise selection process were not included in the final multivariable model.