Table 5.
Participant Characteristics Associated With Full-Field Stimulus Thresholds (FST) White Stimulus
N | FST White Stimulus (dB) Mean ± SD | Univariable Analysis P Value | Multivariable Analysis P Value | |
All | 93 | −32 ± 13 | ||
Clinical diagnosis | <0.001 | <0.001 | ||
USH2 | 56 | −26 ± 10 | ||
ARRP | 37 | −39 ± 13 | ||
Age at enrollment , y | 0.61a | NAb | ||
<30 y | 20 | −33 ± 9 | ||
30 to < 40 y | 26 | −31 ± 12 | ||
40 to < 50 y | 27 | −32 ± 15 | ||
≥50 y | 20 | −30 ± 15 | ||
Gender | 0.53 | 0.04 | ||
Female | 51 | −31 ± 12 | ||
Male | 42 | −32 ± 14 | ||
Duration of disease, y c | <0.001a | <0.001a | ||
<10 | 27 | −40 ± 11 | ||
10 to < 20 | 33 | −33 ± 11 | ||
≥20 | 33 | −22 ± 9 | ||
Race/ethnicity | 0.53 | NAb | ||
Non-Hispanic white | 84 | −32 ± 13 | ||
Other | 9 | −29 ± 10 | ||
Smoking status | ||||
Ever smoked daily | 26 | −31 ± 13 | 0.94 | NAb |
Never smoked daily | 67 | −32 ± 13 | ||
Dietary supplement use | ||||
None | 35 | −32 ± 12 | 0.55 | NAb |
Vitamin A only | 8 | −33 ± 13 | ||
DHA only | 5 | −24 ± 6 | ||
Lutein only | 5 | −37 ± 9 | ||
Multiple supplements | 40 | −31 ± 15 |
Variable was analyzed as continuous.
Factors with P values > 0.05 in the stepwise selection process were not included in the final multivariable model.
Computed from age of onset (a participant-reported field based on their awareness of visual symptoms) and date of enrollment.