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. 2020 Sep 29;11:558894. doi: 10.3389/fphar.2020.558894

Table 1.

Cytotoxicities of the artemisinins against cancer cell lines in vitro.ab

Compound HEK293 MCF-7 UACC62 TK 10
IC50 µM
Artemisinin 2 120.70 ± 1.07 ND ND ND
Artemisone 4 86.72 ± 1.09 2.75 ± 0.79 32.7 ± 3.47 >100
Geranylpiperazine-DHA 6 24.26 ± 1.15 ND ND ND
Farnesylpiperazine-DHA 7 35.46 ± 1.09 1.56 ± 0.51 2.15 ± 0.79 3.00 ± 0.67
a

HEK293 human embryonic kidney; MCF-7 breast; UACC62 melanoma; TK10 renal cancer cell lines.

b

Results are reported as inhibitory concentrations IC50 from three independent biological replicates, each performed as technical replicates ± standard deviation (SD).