Table 2.
Chromosome | Peak Position (Mb) | Region (Mb)a | Max IBD % | Notesb |
---|---|---|---|---|
1 | 76.61 | 74.86–77.27 (1p31.1) | 0.0218 | ST6GALNAC3 (MIM: 610133) (76.54–77.10) is subject to virus-driven selective pressure81 |
1 | 152.93 | 151.75–153.65 (1q21.3) | 0.0214 | epidermal differentiation complex locus (151.96–153.60);82 the locus with the greatest differentiation between humans and chimpanzees;83 recent positive selection in humans80 |
4 | 184.59 | 184.30–185.39 (4q35.1) | 0.0217 | – |
5 | 2.72 | 2.32–2.98 (5p15.33) | 0.0221 | – |
16 | 18.08 | 17.36–18.58 (16p12.3) | 0.0244 | – |
17 | 36.05 | 35.18–36.51 (17q12) | 0.0239 | HNF1B (MIM: 189907) (36.05–36.10, previously known as TCF2) is associated with diabetes84,85 |
Regions with maximum IBD rate between 0.021% and 0.025% are shown. Positions (in Mb) are in GRCh37 coordinates.
Region in which the IBD rate is at least 80% of the value at the peak.
Genes listed within this column are contained with the region given in the third column.