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. 2020 Oct 13;107(5):895–910. doi: 10.1016/j.ajhg.2020.09.010

Table 2.

Secondary Regions from UK Biobank Selection Scan

Chromosome Peak Position (Mb) Region (Mb)a Max IBD % Notesb
1 76.61 74.86–77.27 (1p31.1) 0.0218 ST6GALNAC3 (MIM: 610133) (76.54–77.10) is subject to virus-driven selective pressure81
1 152.93 151.75–153.65 (1q21.3) 0.0214 epidermal differentiation complex locus (151.96–153.60);82 the locus with the greatest differentiation between humans and chimpanzees;83 recent positive selection in humans80
4 184.59 184.30–185.39 (4q35.1) 0.0217
5 2.72 2.32–2.98 (5p15.33) 0.0221
16 18.08 17.36–18.58 (16p12.3) 0.0244
17 36.05 35.18–36.51 (17q12) 0.0239 HNF1B (MIM: 189907) (36.05–36.10, previously known as TCF2) is associated with diabetes84,85

Regions with maximum IBD rate between 0.021% and 0.025% are shown. Positions (in Mb) are in GRCh37 coordinates.

a

Region in which the IBD rate is at least 80% of the value at the peak.

b

Genes listed within this column are contained with the region given in the third column.