Table 3B.

Quarterly (Q1 2014–Q4 2017), annual (2014–2017), and cumulative rate of past 30-day abuse per 100 ASI-MV assessments adjusted for tablets dispensed

Time	Tapentadol ER		ADF ER Opioids		Non-ADF ER Opioids
	Estimate	95% CI	Estimate	95% CI	Estimate	95% CI
Quarter
Q1 2014	0.007	0.002–0.030	0.071	0.065–0.078	0.046	0.042–0.050
Q2 2014	0.004	0.000–0.025	0.082	0.075–0.089	0.045	0.042–0.049
Q3 2014	0.013	0.005–0.036	0.084	0.077–0.091	0.046	0.042–0.050
Q4 2014	0.021	0.009–0.046	0.089	0.081–0.097	0.045	0.041–0.049
Q1 2015	0.006	0.002–0.025	0.074	0.067–0.081	0.044	0.040–0.048
Q2 2015	0.010	0.004–0.026	0.044	0.039–0.049	0.038	0.035–0.041
Q3 2015	0.010	0.004–0.026	0.056	0.051–0.062	0.046	0.043–0.050
Q4 2015	0.008	0.003–0.025	0.054	0.048–0.060	0.048	0.044–0.052
Q1 2016	0.006	0.001–0.022	0.056	0.050–0.062	0.047	0.043–0.051
Q2 2016	0.010	0.004–0.027	0.054	0.048–0.060	0.045	0.041–0.049
Q3 2016	0.005	0.001–0.020	0.052	0.046–0.059	0.044	0.040–0.048
Q4 2016	0.006	0.001–0.023	0.058	0.051–0.066	0.047	0.043–0.052
Q1 2017	0.006	0.002–0.025	0.066	0.059–0.074	0.047	0.042–0.052
Q2 2017	0.003	0.000–0.024	0.057	0.050–0.065	0.049	0.044–0.054
Q3 2017	0.007	0.002–0.027	0.056	0.048–0.064	0.046	0.041–0.051
Q4 2017	0.020	0.008–0.047	0.072	0.063–0.082	0.050	0.044–0.056
Year
2014	0.011	0.007–0.020	0.081	0.078–0.085	0.045	0.043–0.047
2015	0.009	0.005–0.015	0.056	0.054–0.059	0.044	0.042–0.046
2016	0.007	0.004–0.012	0.055	0.052–0.058	0.046	0.044–0.048
2017	0.009	0.005–0.016	0.062	0.058–0.067	0.048	0.045–0.050
Cumulative	0.009	0.006–0.011	0.064	0.062–0.066	0.045	0.044–0.046

ADF = abuse-deterrent formulation; ASI-MV= Addiction Severity Index–Multimedia Version; CI = confidence interval; ER = extended-release.