Table 4.

Cumulative rate of route of administration

	Tapentadol ER N = 46		ADF ER Opioids N = 5,313		Non-ADF ER Opioids N = 7,192
ROA	Estimate	95% CI	Estimate	95% CI	Estimate	95% CI
Swallow whole	58.70	38.68–85.70	53.81	52.48–55.18	34.99	33.90–36.12
Other oral	17.39	7.50–34.26	23.50	22.39–24.68	11.30	10.59–12.06
Inject	10.87	3.52–25.33	26.08	24.92–27.29	42.85	41.71–44.02
Snort	2.17	0.06–12.11	29.30	28.09–30.55	38.95	37.83–40.10
Other	8.70	2.37–22.26	3.51	3.04–4.04	5.04	4.56–5.58
Smoke	0.00	0.00–0.00	3.37	2.92–3.90	1.25	1.02–1.54

ADF = abuse-deterrent formulation; CI = confidence interval; ER = extended-release; ROA = route of administration.