Figure 1.

Histological sections of Control and iohexol-treated rat kidneys stained with haematoxylin and eosin (H&E) stain. Control rat displays a normal morphology with a well-preserved glomerulus (notched black arrow) surrounded by clearly demarcated tubules (arrow pentagon). Experimental rats (2 h through 12 h) demonstrate acute tubular injury with tubular dilatation and degeneration of segments of epithelial cells (thin black arrows). Others have flattened, regenerating-type epithelial cells (thick black arrow) and some show frank necrosis (notched black arrow). Most tubules appear normal at 24 h. Scale bar = 450 µm. (A color version of this figure is available in the online journal.)