Table 2.
Variables |
Iron parameters |
Vitamin D |
Oxidative stress |
AKI | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | ||
Iron parameters | 1. Serum iron | 1 | |||||||||||||||
2. TSAT | 0.232 | 1 | |||||||||||||||
3. Serum ferritin | .379* | 0.052 | 1 | ||||||||||||||
4. Serum hepcidin | −0.316 | 0.216 | −.667** | 1 | |||||||||||||
5. Hemoglobin | 0.197 | −.345* | .346* | −0.287 | 1 | ||||||||||||
6. Haptoglobin | 0.241 | −0.008 | 0.012 | −0.205 | 0.307 | 1 | |||||||||||
7. Serum CPK | 0.258 | 0.124 | −.452** | .385* | −.503** | −0.07 | 1 | ||||||||||
8. Serum catalytic iron | .439** | −0.065 | .472** | −.856** | 0.026 | 0.188 | −0.19 | 1 | |||||||||
9. Urine catalytic iron | .454** | −0.15 | .806** | −.679** | .633** | 0.235 | −.563** | .517** | 1 | ||||||||
Vit D | 10. 25(OH)D3 | −.374* | −0.083 | 0.304 | −0.171 | −0.015 | −0.24 | −.685** | 0.123 | 0.293 | 1 | ||||||
11. 1,25(OH)2D3 | 0.233 | 0.029 | .765** | −.795** | 0.027 | −0.045 | −.498** | .784** | .649** | .481** | 1 | ||||||
Oxidative stress | 12. Tissue peroxidation | .489** | 0.225 | 0.301 | 0.045 | 0.12 | 0.19 | −0.024 | 0.004 | .469** | 0.175 | 0.05 | 1 | ||||
13. Tissue thiol | −0.01 | −0.078 | −.720** | .489** | 0.009 | 0.076 | .569** | −.368* | −.611** | −.647** | −.814** | −0.243 | 1 | ||||
14. Catalase | 0.035 | −0.149 | −.558** | 0.195 | −0.085 | 0.038 | .658** | −0.074 | −.580** | −.734** | −.528** | −.556** | .832** | 1 | |||
15. SOD | 0.06 | −0.146 | −0.218 | .363* | .635** | 0.234 | −0.153 | −.453** | 0.1 | −0.138 | −.591** | .366* | .494** | 0.048 | 1 | ||
AKI | 16. Urinary NGAL | .506** | 0.142 | .699** | −.432** | 0.144 | 0.119 | −0.308 | .410* | .788** | .401* | .609** | .787** | −.712** | −.780** | −0.074 | 1 |
TSA: transferrin saturation; CPK: creatine phosphokinase; Vit D: vitamin D; 25(OH)D3: 25-dihyrdoxyvitamin D3; 1,25(OH)2D3: 1,25-dihydroxyvitamin D3; SOD: superoxide dismutase; NGAL: neutrophil gelatinase-associated lipocalin
*P < 0.05, ** P < 0.01, ***P < 0.001 (2-tailed), Pearson correlation coefficients (n = 36).