TABLE 5.
Association Between Chlamydia Status and Getting Pregnant Among Women With a Pregnancy Intention Stratified by Age at Time of Attempting to Conceive
| Planned Pregnancies | Time | Crude HR | aHR | |||||
|---|---|---|---|---|---|---|---|---|
| n* | Person-Months† | HR | 95% CI | P | aHR | 95% CI | P | |
| 1. Age 16–29 y | ||||||||
| Chlamydia negative | 709 | 3871 | 1 | 1 | ||||
| Chlamydia positive | 162 | 1374 | 0.78 | 0.66–0.92 | <0.01 | 0.79 | 0.67–0.94 | <0.01 |
| No infection | 709 | 3871 | 1 | 1 | ||||
| 1 infection | 132 | 1069 | 0.80 | 0.67–0.97 | 0.01 | 0.81 | 0.68–0.97 | 0.02 |
| Multiple infections | 30 | 305 | 0.71 | 0.49–1.03 | 0.07 | 0.71 | 0.49–1.03 | 0.07 |
| 2. Age 30–32 y | ||||||||
| Chlamydia negative | 425 | 2162 | 1 | 1 | ||||
| Chlamydia positive | 98 | 692 | 0.72 | 0.59–0.89 | <0.01 | 0.74 | 0.60–0.92 | <0.01 |
| No infection | 425 | 2162 | 1 | 1 | ||||
| 1 infection | 79 | 571 | 0.72 | 0.58–0.90 | <0.01 | 0.75 | 0.59–0.94 | 0.01 |
| Multiple infections | 19 | 121 | 0.71 | 0.45–1.13 | 0.15 | 0.72 | 0.45–1.14 | 0.16 |
| 3. Age 33–39 y | ||||||||
| Chlamydia negative | 485 | 3649 | 1 | 1 | ||||
| Chlamydia positive | 131 | 842 | 1.07 | 0.89–1.28 | 0.48 | 1.07 | 0.89–1.28 | 0.49 |
| No infection | 485 | 3649 | 1 | 1 | ||||
| 1 infection | 115 | 690 | 1.11 | 0.92–1.34 | 0.29 | 1.10 | 0.90–1.33 | 0.35 |
| Multiple infections | 16 | 152 | 0.81 | 0.49–1.34 | 0.42 | 0.85 | 0.50–1.42 | 0.52 |
Chlamydia positive was defined as a positive NAAT test outcome in the CSI study (CSI-NAAT), and/or the presence of chlamydia IgG and/or a self-reported chlamydia infection. For these analyses, multiple imputations were used to estimate time of first chlamydia infection in women without a known first year of chlamydia infection. Analyses were stratified for age categories based on tertiles. All models were adjusted for age at pregnancy/trying to get pregnant and migration background.
*Complete cases.
†Person-months of complete cases.
aHR indicates adjusted hazard ratio; CI, confidence interval; HR, hazard ratio.