Table 1. Summary of Key Analysis Assumptions Used to Estimate the Effects of Colorectal Cancer and Women’s Breast and Cervical Cancers in the United States.

Analysis Assumption	Breast Cancer	Cervical Cancer	Colorectal Cancer
Study cohort	50-year-old women	21-year-old women	50-year-old men and women
Screening agea	50–74 y	21–65 y	50–75 y
Eligible US population for the test (million)b	48.7	96.7	95.9
Follow-up period	Lifetime or until death by any cause
Screening tests includeda	Mammogram	Cytology or pap smear	High-sensitivity FOBT, flexible sigmoidoscopy, or colonoscopy
Screening intervalsa	Every 2 years	Every 3 years	Annual screening with high-sensitivity FOBT Sigmoidoscopy every 5 years, with high-sensitivity FOBT every 3 years Screening colonoscopy every 10 years
Baseline screening rate (%)c	78.3	79.9	67.7
Age eligible US population screened in baseline (millions)b	37.4	76.8	63.5
Other screening scenarios (number of additional people needed to be screened to reach the goal [in millions] by cancer typeb)	Increase in baseline rate by 10 percentage points (breast, 4.8; cervical, 9.6; colorectal, 9.4) Screening rate of 90% (breast, 5.6; cervical, 9.7; colorectal, 20.9) Screening rate of 100% (breast, 10.4; cervical, 19.3; colorectal, 30.3)

Abbreviations: BRFSS, Behavioral Risk Factor Surveillance System; FOBT, fecal occult blood test.

^a Based on US Preventive Services Task Force recommendations, 2008.

^b Author calculations based on annual estimates of the resident population by sex, race, and Hispanic origin for 2016 from the US Census.

^c Based on BRFSS 2016 data (7).