Table 2. Therapeutic interventions to correct pathological coagulation parameters.
Laboratory scenario | Correction |
---|---|
Platelets <80.000–100.000/μl, decreased MCFex, MCFex-MCFfib <30, MCEex-MCEfib <142 | Platelet concentrate |
Decreased PTI and/or an increase in CTex> 79 sec. | fresh frozen plasma, prothrombin complex concentrate |
Decreased fibrinogen, decreased MCFfib | Cryoprecipitate, fibrinogen concentrate |
Difference between ARTEM/EXTEM-A10 more than 10% | Tranexamic acid |
Decreased Antithrombin III less than 60% | AT-III |
Note: MCFex—maximum clot firmness extem; MCFfib—maximum clot firmness fibtem; MCEfib—maximum clot elasticity.