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. 2020 Oct 13;15(10):e0240117. doi: 10.1371/journal.pone.0240117

Table 2. Therapeutic interventions to correct pathological coagulation parameters.

Laboratory scenario Correction
Platelets <80.000–100.000/μl, decreased MCFex, MCFex-MCFfib <30, MCEex-MCEfib <142 Platelet concentrate
Decreased PTI and/or an increase in CTex> 79 sec. fresh frozen plasma, prothrombin complex concentrate
Decreased fibrinogen, decreased MCFfib Cryoprecipitate, fibrinogen concentrate
Difference between ARTEM/EXTEM-A10 more than 10% Tranexamic acid
Decreased Antithrombin III less than 60% AT-III

Note: MCFex—maximum clot firmness extem; MCFfib—maximum clot firmness fibtem; MCEfib—maximum clot elasticity.