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. 2020 Sep 24;16(9):e1009040. doi: 10.1371/journal.pgen.1009040

Fig 1. Pou4f3(Δ/+) mice display progressive hearing loss.

Fig 1

(A-C) 2 months (n = 9–10), (D-F) 3 months (n = 14–16) and (G-I) 7 months (n = 8 each) old wildtype Pou4f3(+/+) and mutant Pou4f3(Δ/+) mice were tested with DPOAE and ABR. (A, D, G) DPOAE thresholds; (B, E, H) ABR thresholds; (C, F, I) ABR peak 1 (P1) amplitudes. * P < 0.05, ** P < 0.01 and *** P < 0.001 by two-way ANOVA. (J) ABR waveforms of 3 months old Pou4f3(+/+) and Pou4f3(Δ/+) mice at 32 kHz. Data were mean of n = 14–16 animals. ABR thresholds of each genotype were highlighted. dB, decibel; SPL, sound pressure level.