Table 6. Average computational times for compared approaches.

	SSO			EPSO			LKHM
Threshold	Fruitfly	Mouse	Human	Fruitfly	Mouse	Human	Fruitfly	Mouse	Human
0.050	4.4*	71.2	731.6	5.4	148.6	710.2	0.7	71.5	421.2
0.055	4.0	69.4	501.4	4.0	167.4	650.0	0.7	71.5	421.2
0.060	4.0	75.6	451.8	5.0	163.2	637.8	0.7	71.5	421.2
0.065	4.0	73.6	407.6	5.0	168.0	683.8	0.7	71.5	421.2
0.070	4.0	107.4	418.8	5.0	146.0	629.6	0.7	71.5	421.2
0.075	4.0	78.0	375.6	5.0	168.0	758.2	0.7	71.5	421.2
0.080	4.0	74.6	395.2	5.0	166.4	751.2	0.7	71.5	421.2
0.085	4.0	76.4	402.0	5.0	167.2	771.2	0.7	71.5	421.2
Total Ave.	4.0	78.2	460.5	4.9	161.8	699.0	0.7	71.5	421.2

* CPU time in second.