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Curve-shift beta-arrestin2 recruitment assay of D2R antagonism resulting from preapplication of SWR-1-8, SV-III-130, and SWR-1-14. Curve-shift experiments for DA-induced beta-arrestin2 recruitment to D2R following 5 min preincubation with A) SWR-1-8, B) SV-III-130, and C) SWR-1-14. The normalized data represent mean values from three independent experiments (n = 3) performed in triplicate. The curves represent the best fit to the data using nonlinear regression analysis.
