Table 1.
Patient Demographics and Contributing Factors for Ovarian Conservation (N=86,005)
| Ovarian Conservation | Oophorectomy | Adjusted OR* (95% CI) | P | |
|---|---|---|---|---|
| n | 4,109 (4.8) | 81,896 (95.2) | ||
| Age (y) | 58.4±15.0 | 61.6±11.6 | ||
| 50 or older | 2,867 (3.9) | 70,278 (96.1) | 1 | |
| 40–49 | 734 (7.5) | 9,116 (92.5) | 1.90 (1.75–2.08) | <.001 |
| Younger than 40 | 508 (16.9) | 2,502 (83.1) | 4.78 (4.29–5.33) | <.001 |
| Ethnicity | ||||
| White | 3,141 (4.6) | 65,732 (95.4) | 1 | |
| Black | 205 (5.2) | 3,762 (94.8) | 1.10 (0.95–1.28) | .20 |
| Hispanic | 437 (6.6) | 6,153 (93.4) | 1.16 (1.03–1.29) | .011 |
| Asian | 219 (4.5) | 4,673 (95.5) | 0.81 (0.70–0.94) | .006 |
| Others | 84 (5.9) | 1,329 (94.1) | 0.92 (0.73–1.16) | .48 |
| Unknown | 23 (8.5) | 247 (91.5) | 1.69 (1.09–2.62) | .018 |
| Marital status | ||||
| Single | 595 (4.8) | 11,909 (95.2) | 1 | |
| Others | 3,306 (4.7) | 66,372 (95.3) | 1.06 (0.97–1.16) | .18 |
| Unknown | 208 (5.4) | 3,615 (94.6) | 1.20 (1.01–1.43) | .042 |
| Registry area | ||||
| West | 2,212 (4.9) | 42,971 (95.1) | 1 | |
| Central | 863 (4.4) | 18,535 (95.6) | 0.89 (0.82–0.97) | .009 |
| East | 1,034 (4.8) | 20,390 (95.2) | 1.01 (0.93–1.09) | .88 |
| Year of diagnosis | ||||
| 1983–1989 | 435 (5.4) | 7,584 (94.6) | 1 | |
| 1990–1999 | 938 (4.9) | 18,037 (95.1) | 0.90 (0.80–1.02) | .10 |
| 2000–2009 | 2,067 (4.7) | 41,604 (95.3) | 0.84 (0.75–0.94) | .002 |
| 2010–2012 | 669 (4.4) | 14,671 (95.6) | 0.81 (0.71–0.93) | .002 |
| Stage | ||||
| IA | 3,315 (4.8) | 65,153 (95.2) | 0.94 (0.85–1.05) | .30 |
| IB | 390 (3.7) | 10,188 (96.3) | 1 | |
| I NOS | 404 (5.8) | 6,555 (94.2) | 1.01 (0.87–1.17) | .89 |
| Histology | ||||
| Grade 1 endometrioid | 3,045 (5.7) | 50,357 (94.3) | 1.62 (1.50–1.74) | <.001 |
| Grade 2 endometrioid | 1,064 (3.3) | 31,539 (96.7) | 1 | |
| Tumor size (cm) | ||||
| 2.0 or less | 974 (5.9) | 15,438 (94.1) | 1.96 (1.55–2.49) | <.001 |
| 2.1–4.0 | 534 (3.4) | 15,351 (96.6) | 1.23 (0.97–1.57) | .09 |
| 4.1–6.0 | 199 (3.1) | 6,317 (96.9) | 1.06 (0.82–1.39) | .65 |
| Greater than 6.0 | 80 (3.2) | 2,427 (96.8) | 1 | |
| Unknown | 2,322 (5.2) | 42,363 (94.8) | 1.71 (1.36–2.16) | <.001 |
OR, odds ratio; CI, confidence interval; NOS, not otherwise specified.
Data are n (%) or mean±standard deviation unless otherwise specified.
Percentages are shown per row. A binary logistic regression model was used for multivariable analysis. All patient factors and tumor characteristics were entered in the final model.
Bold indicates a significant P value.
*
OR for ovarian conservation compared with oophorectomy.